RLR Genes
Choose from InvivoGen's collection of native or engineered RLR genes
InvivoGen offers a list of genes related to the RIG-I-like receptor (RLR) pathway. These genes can be provided in their native form, or modified by adding tags or creating dominant negative variants to facilitate diverse experimental applications.
RIG-I-like receptors (RLRs) are a family of three cytoplasmic RNA helicases that are critical for the effective immune response against viruses through the sensing of cytoplasmic RNA. They recognize double-stranded RNA produced during virus replication or from synthetic sources.
Key features of InvivoGen's RLR genes
- Fully sequenced genes from human or mouse
- Selectable in both bacterial and mammalian cells
- Simple to subclone due to unique restriction sites
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Choice of native or engineered genes (Tagged, dominant negative version)
Given their role in antiviral immunity, RLRs are being explored for their potential to boost antiviral responses in chronic infections or to enhance the efficacy of vaccines. Understanding their role is essential for developing new therapeutic strategies, particularly in infectious diseases, cancer, and autoimmunity.
Read our review on RIG-I-Like Receptors
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