C-type Lectin Receptors
InvivoGen provides an extensive list of tools to study C-type lectin receptors
C-type lectin receptors (CLRs) comprise a large family of receptors that bind to carbohydrates in a calcium-dependent manner. CLRs include the Dendritic cell-associated C-type lectin-1 (Dectin-1), Dectin-2, macrophage-inducible C-type lectin (Mincle), DC-specific intercellular adhesion molecule-grabbing nonintegrin (DC-SIGN), DC-SIGN-related protein (DC-SIGNR), and mannose-binding lectin (MBL). CLRs are involved in fungal, bacterial, and viral recognition and thus, play an important role in the modulation of the innate immune response.
These receptors share one or more carbohydrate-recognition domains (CRD) in order to bind specific carbohydrate structures on the surface of pathogens. This binding is essential for the immune system to identify and initiate appropriate responses to these pathogens, leading to their clearance from the body.
Choose from our growing collection
- CLR reporter cells
- A large choice of CLR agonists
- CLR inhibitor
- CLR antibodies for detection or neutralization
- Fully sequenced CLR genes and isoforms
Key features of InvivoGen's products
- Each lot is functionally tested
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Guaranteed free of unwanted bacterial contaminants
